ECT for Treatment-Resistant Depression
June 19, 2025

Depression can feel like a relentless battle, especially when traditional treatments don’t bring the relief you need. For those grappling with treatment-resistant depression, it can seem like there’s no way out. Fortunately, Electroconvulsive Therapy (ECT) can offer a beacon of hope. But what is ECT, and how does it work for depression?
Understanding Treatment-Resistant Depression
What Is Treatment-Resistant Depression?
Treatment-resistant depression is a term used when a person’s depression does not improve after trying at least two different antidepressants. It can be disheartening, but recognizing this condition is vital in seeking alternative treatments.
Why Some Treatments Fail
Depression’s complexity means that sometimes medications or therapies that work for one person may not work for another. Factors like genetics, environmental influences and brain chemistry all play a role in how depression shows up and responds to treatment.
What Is Electroconvulsive Therapy?
The Basics of ECT
Electroconvulsive Therapy, or ECT, is a medical treatment where controlled electrical currents are passed through the brain. This process aims to trigger a brief seizure, altering brain chemistry and helping alleviate severe depression symptoms.
Is Electroconvulsive Therapy Effective?
ECT has been shown to be highly effective for individuals with severe depression, especially those who haven’t responded to other treatments. It’s often considered when rapid improvement is needed, such as in cases of severe suicidal ideation or when other treatments have failed.
How Does ECT Work for Depression?
The ECT Procedure
During ECT, patients are placed under general anesthesia for comfort. Electrodes are applied to the scalp, and a carefully controlled electric current is delivered. This induces a short seizure, usually lasting less than a minute.
How ECT Affects the Brain
The exact mechanism of how ECT alleviates depression isn’t fully understood, but it is believed to cause changes in brain neurotransmitters and improve communication between different parts of the brain. These changes can lead to mood stabilization and relief from depressive symptoms.
Benefits and Risks of ECT
Benefits of ECT
- Rapid Symptom Relief: ECT can provide quick relief from severe depression symptoms, which is crucial for those at risk of self-harm.
- High Success Rate: Studies show that ECT can be more effective than medication for treatment-resistant depression, with success rates between 70% to 90%.
- Potential to Improve Life Quality: For many, ECT can bring significant improvements in mood, energy levels and overall quality of life.
Risks and Side Effects
- Memory Issues: Some patients experience memory loss, particularly around the time of treatment. However, this is usually temporary.
- Physical Side Effects: ECT can cause short-term side effects like headache, muscle aches or nausea, but these are generally mild.
- Anesthesia Risks: As with any procedure involving anesthesia, there are inherent risks, although they are minimal with ECT.
What to Consider With ECT
Discuss With Your Doctor
If you’re considering ECT, it’s important to have an open discussion with your healthcare provider. They can help you weigh the benefits and risks, considering your medical history and current condition.
Preparing for ECT
Preparation involves a thorough medical evaluation to see if you’re a suitable candidate. Your doctor will explain the procedure, what to expect and how to prepare, including any changes to medication or dietary restrictions before treatment.
Post-ECT Care
After ECT, you may need to rest and recuperate. Follow-up care is vital, including potential psychotherapy or medications to maintain improvements and prevent relapse.
Comparing ECT to Other Treatments
ECT vs Medication
While medications are often the first line of treatment, ECT is an option when medications fail. ECT can act faster than drugs, which is vital for severe cases.
ECT vs Psychotherapy
Psychotherapy is beneficial for many with depression, but ECT may be recommended when therapy alone isn’t effective, particularly for treatment-resistant cases.
About Central Florida Behavioral Hospital
Central Florida Behavioral Hospital is a homelike facility that offers treatment to children, adolescents and adults suffering from mental health and substance abuse disorders. Located in Orlando, FL, our nine acre campus provides a serene and therapeutic environment, perfect for healing and growth.
We offer high-quality care with all of our services that also comes with a supportive staff. Some of our services include our inpatient, outpatient, children’s, adolescent and general adult programs. All of these programs feature evidence-based therapies and are designed to meet the individual needs of our patients.
To schedule a no-cost assessment or for more information, please call 407-370-0111.
Individual results may vary. There are risks associated with any medical procedure. Talk with your doctor about these risks to find out if electroconvulsive therapy (ECT) is right for you.
About Central Florida Behavioral Hospital
Central Florida Behavioral Hospital is a homelike facility that offers treatment to children, adolescents and adults suffering from mental health and substance abuse disorders. Located in Orlando, FL, our nine acre campus provides a serene and therapeutic environment, perfect for healing and growth.
We offer high-quality care with all of our services that also comes with a supportive staff. Some of our services include our inpatient, outpatient, children’s, adolescent and general adult programs. All of these programs feature evidence-based therapies and are designed to meet the individual needs of our patients.
To schedule a no-cost assessment or for more information, please call 407-370-0111.